Membrane Sterols Modulate the Binding Mode of Amphotericin B without Affecting Its Affinity for a Lipid Bilayer

Membrane-active antibiotics are known to selectively target certain pathogens based on cell membrane properties, such as fluidity, lipid ordering, and phase behavior. These are in turn modulated by the composition of a lipid bilayer and in particular by the presence and type of membrane sterols. Amp...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 32(2016), 14 vom: 12. Apr., Seite 3452-61
1. Verfasser: Neumann, Anna (VerfasserIn)
Weitere Verfasser: Wieczor, Milosz, Zielinska, Joanna, Baginski, Maciej, Czub, Jacek
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Lipid Bilayers Amphotericin B 7XU7A7DROE Cholesterol 97C5T2UQ7J Dimyristoylphosphatidylcholine U86ZGC74V5 Ergosterol Z30RAY509F