Managing the protein folding demands in the endoplasmic reticulum of plants

© 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 211(2016), 2 vom: 11. Juli, Seite 418-28
1. Verfasser: Liu, Jian-Xiang (VerfasserIn)
Weitere Verfasser: Howell, Stephen H
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Review Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. autophagy endoplasmic reticulum (ER) endoplasmic reticulum-associated protein degradation (ERAD) environmental stress responses programmed cell death (PCD) protein folding mehr... reproductive development unfolded protein response (UPR)
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520 |a Endoplasmic reticulum (ER) stress occurs in plants during certain developmental stages or under adverse environmental conditions, as a result of the accumulation of unfolded or misfolded proteins in the ER. To minimize the accumulation of misfolded proteins in the ER, a protein quality control (PQC) system monitors protein folding and eliminates misfolded proteins through either ER-associated protein degradation (ERAD) or autophagy. ER stress elicits the unfolded protein response (UPR), which enhances the operation in plant cells of the ER protein folding machinery and the PQC system. The UPR also reduces protein folding demands in the ER by degrading mRNAs encoding secretory proteins. In plants subjected to severe or chronic stress, UPR promotes programmed cell death (PCD). Progress in the field in recent years has provided insights into the regulatory networks and signaling mechanisms of the ER stress responses in plants. In addition, novel physiological functions of the ER stress responses in plants for coordinating plant growth and development with changing environment have been recently revealed 
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650 4 |a Research Support, Non-U.S. Gov't 
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650 4 |a autophagy 
650 4 |a endoplasmic reticulum (ER) 
650 4 |a endoplasmic reticulum-associated protein degradation (ERAD) 
650 4 |a environmental stress responses 
650 4 |a programmed cell death (PCD) 
650 4 |a protein folding 
650 4 |a reproductive development 
650 4 |a unfolded protein response (UPR) 
700 1 |a Howell, Stephen H  |e verfasserin  |4 aut 
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