Erythrocyte osmotic fragility and select hematologic variables in postparturient mares and their foals

© 2016 American Society for Veterinary Clinical Pathology.

Détails bibliographiques
Publié dans:Veterinary clinical pathology. - 1975. - 45(2016), 2 vom: 12. Juni, Seite 260-70
Auteur principal: Arfuso, Francesca (Auteur)
Autres auteurs: Quartuccio, Marco, Bazzano, Marilena, Fazio, Francesco, Piccione, Giuseppe
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Veterinary clinical pathology
Sujets:Journal Article Erythrocyte osmotic resistance hemolysis neonatal period red blood cells
Description
Résumé:© 2016 American Society for Veterinary Clinical Pathology.
BACKGROUND: Knowledge of hematologic function in postparturient mares and foals is crucial for the monitoring of their health status and for the prompt diagnosis of pathologic conditions
OBJECTIVES: The aim of this study was to evaluate erythrocyte osmotic fragility (EOF) and select hematologic variables in mares and their foals during the first month after foaling
METHODS: Blood samples were collected from each animal every 3 days from day 1 until day 30 after foaling, and tested for RBC count, HGB, HCT, MCV, and EOF. Two-way repeated measures analysis of variance (ANOVA) and Bonferroni post hoc comparison test were applied to determine the effects of time and age (mares vs foals). Pearson correlation coefficients were computed for EOF and time or MCV values
RESULTS: There was a significant effect of time in RBC, HGB, HCT, and EOF (P < .001). Statistically significant differences were observed between mares and foals for RBC, MCV, and EOF (P < .05) throughout the experimental period. Significant correlations between EOF and both time and MCV (P < .05) were found in mares as well as in foals
CONCLUSION: These results contribute to the understanding of perinatal changes in hematologic variables in mares and foals. In addition, the data support the relevance of specific reference intervals for postparturient mares and foals. The findings also provide useful information that could help clinicians to better interpret clinical data and diagnose equine disease
Description:Date Completed 04.04.2017
Date Revised 04.04.2017
published: Print-Electronic
Citation Status MEDLINE
ISSN:1939-165X
DOI:10.1111/vcp.12344