Diabetic Macular Edema Diagnosis and Treatment in the Real World : An Analysis of Medicare Claims Data (2008 to 2010)

Copyright 2016, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 47(2016), 3 vom: 03. März, Seite 258-67
1. Verfasser: Dugel, Pravin U (VerfasserIn)
Weitere Verfasser: Layton, Andrew, Varma, Rohit B
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Angiogenesis Inhibitors VEGFA protein, human Vascular Endothelial Growth Factor A
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500 |a Date Revised 30.12.2016 
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500 |a Citation Status MEDLINE 
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520 |a BACKGROUND AND OBJECTIVE: To characterize vascular endothelial growth factor (VEGF) inhibitor treatment patterns in patients with diabetic macular edema (DME) using a Medicare Standard Analytic Files Part B or Outpatient Claims database to understand treatment frequency and DME persistence 
520 |a PATIENTS AND METHODS: A retrospective analysis of treatment patterns for patients diagnosed with DME receiving their first anti-VEGF injection was performed 
520 |a RESULTS: The average number of anti-VEGF injection claims for DME per patient rose from 3.1 to 4.6 per year (mean: 4.2). Within 1 year of diagnosis, 46% of patients received their final DME diagnosis (mean: 1.9 anti-VEGF claims), and 65% of patients received their final anti-VEGF treatment for DME. Patients who received treatment for DME through years 2 and 3 submitted a mean of four and 7.2 anti-VEGF claims, respectively 
520 |a CONCLUSION: VEGF inhibitor treatment was less frequent than in landmark trials, but did resolve DME in a proportion of patients 
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