Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model
Accumulating evidence indicates that microglial TLR2 and TLR4 play a significant role in nociception. Experiments were conducted to evaluate the contribution of TLR2 and TLR4 and their adaptor molecules to neuropathy and their ability to amplify opioid effectiveness. Behavioral tests (von Frey'...
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Bibliographische Detailangaben
| Veröffentlicht in: | Neural plasticity. - 1998. - 2016(2016) vom: 08., Seite 5238730
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| 1. Verfasser: |
Jurga, Agnieszka M
(VerfasserIn) |
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| Weitere Verfasser: |
Rojewska, Ewelina,
Piotrowska, Anna,
Makuch, Wioletta,
Pilat, Dominika,
Przewlocka, Barbara,
Mika, Joanna |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2016
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Analgesics, Opioid
Lipopolysaccharides
Tlr2 protein, rat
Tlr4 protein, rat
Toll-Like Receptor 2
Toll-Like Receptor 4
Buprenorphine
40D3SCR4GZ |
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