Genome-association analysis of Korean Holstein milk traits using genomic estimated breeding value

OBJECTIVE: Holsteins are known as the world's highest-milk producing dairy cattle. The purpose of this study was to identify genetic regions strongly associated with milk traits (milk production, fat, and protein) using Korean Holstein data

Bibliographische Detailangaben
Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 30(2017), 3 vom: 05. März, Seite 309-319
1. Verfasser: Shin, Donghyun (VerfasserIn)
Weitere Verfasser: Lee, Chul, Park, Kyoung-Do, Kim, Heebal, Cho, Kwang-Hyeon
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article Genome-wide Association Studies (GWAS) Korean Holstein Milk Fat Milk Production Milk Protein
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245 1 0 |a Genome-association analysis of Korean Holstein milk traits using genomic estimated breeding value 
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520 |a OBJECTIVE: Holsteins are known as the world's highest-milk producing dairy cattle. The purpose of this study was to identify genetic regions strongly associated with milk traits (milk production, fat, and protein) using Korean Holstein data 
520 |a METHODS: This study was performed using single nucleotide polymorphism (SNP) chip data (Illumina BovineSNP50 Beadchip) of 911 Korean Holstein individuals. We inferred each genomic estimated breeding values based on best linear unbiased prediction (BLUP) and ridge regression using BLUPF90 and R. We then performed a genome-wide association study and identified genetic regions related to milk traits 
520 |a RESULTS: We identified 9, 6, and 17 significant genetic regions related to milk production, fat and protein, respectively. These genes are newly reported in the genetic association with milk traits of Holstein 
520 |a CONCLUSION: This study complements a recent Holstein genome-wide association studies that identified other SNPs and genes as the most significant variants. These results will help to expand the knowledge of the polygenic nature of milk production in Holsteins 
650 4 |a Journal Article 
650 4 |a Genome-wide Association Studies (GWAS) 
650 4 |a Korean Holstein 
650 4 |a Milk Fat 
650 4 |a Milk Production 
650 4 |a Milk Protein 
700 1 |a Lee, Chul  |e verfasserin  |4 aut 
700 1 |a Park, Kyoung-Do  |e verfasserin  |4 aut 
700 1 |a Kim, Heebal  |e verfasserin  |4 aut 
700 1 |a Cho, Kwang-Hyeon  |e verfasserin  |4 aut 
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