Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 17 vom: 07. Mai, Seite 3313-20
1. Verfasser: Qian, Chenggen (VerfasserIn)
Weitere Verfasser: Yu, Jicheng, Chen, Yulei, Hu, Quanyin, Xiao, Xuanzhong, Sun, Wujin, Wang, Chao, Feng, Peijian, Shen, Qun-Dong, Gu, Zhen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. conjugated polymers drug delivery hypoxia-responsive nanomedicine photodynamic therapy Antineoplastic Agents mehr... Drug Carriers Singlet Oxygen 17778-80-2 Doxorubicin 80168379AG Polyvinyl Alcohol 9002-89-5
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520 |a A light-activated hypoxia-responsive conjugated polymer-based nanocarrier is developed for efficiently producing singlet oxygen ((1) O2 ) and inducing hypoxia to promote release of its cargoes in tumor cells, leading to enhanced antitumor efficacy. This dual-responsive nanocarrier provides an innovative design guideline for enhancing traditional photodynamic therapeutic efficacy integrated with a controlled drug-release modality 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
650 4 |a conjugated polymers 
650 4 |a drug delivery 
650 4 |a hypoxia-responsive 
650 4 |a nanomedicine 
650 4 |a photodynamic therapy 
650 7 |a Antineoplastic Agents  |2 NLM 
650 7 |a Drug Carriers  |2 NLM 
650 7 |a Singlet Oxygen  |2 NLM 
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700 1 |a Yu, Jicheng  |e verfasserin  |4 aut 
700 1 |a Chen, Yulei  |e verfasserin  |4 aut 
700 1 |a Hu, Quanyin  |e verfasserin  |4 aut 
700 1 |a Xiao, Xuanzhong  |e verfasserin  |4 aut 
700 1 |a Sun, Wujin  |e verfasserin  |4 aut 
700 1 |a Wang, Chao  |e verfasserin  |4 aut 
700 1 |a Feng, Peijian  |e verfasserin  |4 aut 
700 1 |a Shen, Qun-Dong  |e verfasserin  |4 aut 
700 1 |a Gu, Zhen  |e verfasserin  |4 aut 
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773 1 8 |g volume:28  |g year:2016  |g number:17  |g day:07  |g month:05  |g pages:3313-20 
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