Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 16 vom: 15. Apr., Seite 3115-3121
1. Verfasser: Ye, Yanqi (VerfasserIn)
Weitere Verfasser: Yu, Jicheng, Wang, Chao, Nguyen, Nhu-Y, Walker, Glenn M, Buse, John B, Gu, Zhen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. diabetes drug delivery microneedles pancreatic cells physiological signals Blood Glucose Insulin
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520 |a An innovative microneedle (MN)-based cell therapy is developed for glucose-responsive regulation of the insulin secretion from exogenous pancreatic β-cells without implantation. One MN patch can quickly reduce the blood-sugar levels (BGLs) of chemically induced type-1 diabetic mice and stabilize BGLs at a reduced level for over 10 h 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
650 4 |a diabetes 
650 4 |a drug delivery 
650 4 |a microneedles 
650 4 |a pancreatic cells 
650 4 |a physiological signals 
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700 1 |a Yu, Jicheng  |e verfasserin  |4 aut 
700 1 |a Wang, Chao  |e verfasserin  |4 aut 
700 1 |a Nguyen, Nhu-Y  |e verfasserin  |4 aut 
700 1 |a Walker, Glenn M  |e verfasserin  |4 aut 
700 1 |a Buse, John B  |e verfasserin  |4 aut 
700 1 |a Gu, Zhen  |e verfasserin  |4 aut 
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