Use of alpha-, beta-Estrogen Receptor as a "new tool" for detection of specific small molecule activity

Use of alpha-, beta-Estrogen Receptor as a "new tool" for detection of specific small molecule activity

Cell-based screening methods for nuclear receptor ligands that use transgenic plant cells expressing a single human NR may have advantages over other eukaryotic systems which express multiple NRs. For example, signal-to-noise ratio might be improved because ligands would be less likely to bind to ot...

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Veröffentlicht in:Plant molecular biology reporter. - 1998. - 33(2015), 6 vom: 01. Dez., Seite 1837-1843
1. Verfasser: Gunjan, Samir Kumar (VerfasserIn)
Weitere Verfasser: Rogers, Dennis Trent, Zhang, Jingxian, Yun, Kil-Young, Falcone, Deane L, Littleton, John
Format: Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Plant molecular biology reporter
Schlagworte:Journal Article Estrogen receptor genetic switch hairy root ligand transgenic