Multigrowth Factor Delivery via Immobilization of Gene Therapy Vectors

Multigrowth Factor Delivery via Immobilization of Gene Therapy Vectors

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 16 vom: 05. Apr., Seite 3145-51
1. Verfasser: Hao, Jie (VerfasserIn)
Weitere Verfasser: Cheng, Kenneth C K, Kruger, Laura G, Larsson, Lena, Sugai, James V, Lahann, Joerg, Giannobile, William V
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural bone morphogenetic proteins drug delivery gene transfer platelet-derived growth factor regenerative medicine tissue regeneration Antibodies, Immobilized Biocompatible Materials Intercellular Signaling Peptides and Proteins
Beschreibung
Zusammenfassung:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Molecules can be immobilized onto biomaterials by a chemical vapor deposition (CVD) coating strategy. Pentafluorophenolester groups react with amine side chains on antibodies, which can selectively immobilize adenoviral vectors for gene delivery of growth factors. These vectors can produce functional proteins within defined regions of biomaterials to produce customizable structures for targeted tissue regeneration
Beschreibung:Date Completed 26.03.2018
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201600027