Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease
Niemann-Pick type C disease is an autosomal recessive storage disorder, characterized by abnormal sequestration of unesterified cholesterol within the late endolysosomal compartment of cells and accumulation of gangliosides and other sphingolipids. Progressive neurological deterioration and insurgen...
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| Veröffentlicht in: | Neural plasticity. - 1998. - 2016(2016) vom: 07., Seite 3830424
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| 1. Verfasser: |
D'Arcangelo, G
(VerfasserIn) |
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| Weitere Verfasser: |
Grossi, D,
Racaniello, M,
Cardinale, A,
Zaratti, A,
Rufini, S,
Cutarelli, A,
Tancredi, V,
Merlo, D,
Frank, C |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2016
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Enzyme Inhibitors
1-Deoxynojirimycin
19130-96-2
miglustat
ADN3S497AZ
Extracellular Signal-Regulated MAP Kinases
EC 2.7.11.24 |
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