Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain

Trisomy of human chromosome 21 in Down syndrome (DS) leads to several phenotypes, such as mild-to-severe intellectual disability, hypotonia, and craniofacial dysmorphisms. These are fundamental hallmarks of the disorder that affect the quality of life of most individuals with DS. Proper brain develo...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Neural plasticity. - 1998. - 2016(2016) vom: 15., Seite 7434191
1. Verfasser:	Lee, Han-Chung (VerfasserIn)
Weitere Verfasser:	Tan, Kai-Leng, Cheah, Pike-See, Ling, King-Hwa
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2016
Zugriff auf das übergeordnete Werk:	Neural plasticity
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Review STAT Transcription Factors Janus Kinases EC 2.7.10.2