The Vitamin A Derivative All-Trans Retinoic Acid Repairs Amyloid-β-Induced Double-Strand Breaks in Neural Cells and in the Murine Neocortex
The amyloid-β peptide or Aβ is the key player in the amyloid-cascade hypothesis of Alzheimer's disease. Aβ appears to trigger cell death but also production of double-strand breaks (DSBs) in aging and Alzheimer's disease. All-trans retinoic acid (RA), a derivative of vitamin A, was already...
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Détails bibliographiques
| Publié dans: | Neural plasticity. - 1998. - 2016(2016) vom: 15., Seite 3707406
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| Auteur principal: |
Gruz-Gibelli, Emmanuelle
(Auteur) |
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| Autres auteurs: |
Chessel, Natacha,
Allioux, Clélia,
Marin, Pascale,
Piotton, Françoise,
Leuba, Geneviève,
Herrmann, François R,
Savioz, Armand |
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| Format: | Article en ligne
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| Langue: | English |
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| Publié: |
2016
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| Accès à la collection: | Neural plasticity
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| Sujets: | Journal Article
Amyloid beta-Peptides
Peptide Fragments
amyloid beta-protein (1-40)
amyloid beta-protein (1-42)
Vitamin A
11103-57-4
Tretinoin
5688UTC01R |
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