The Vitamin A Derivative All-Trans Retinoic Acid Repairs Amyloid-β-Induced Double-Strand Breaks in Neural Cells and in the Murine Neocortex
The amyloid-β peptide or Aβ is the key player in the amyloid-cascade hypothesis of Alzheimer's disease. Aβ appears to trigger cell death but also production of double-strand breaks (DSBs) in aging and Alzheimer's disease. All-trans retinoic acid (RA), a derivative of vitamin A, was already...
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| Veröffentlicht in: | Neural plasticity. - 1998. - 2016(2016) vom: 15., Seite 3707406
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| 1. Verfasser: |
Gruz-Gibelli, Emmanuelle
(VerfasserIn) |
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| Weitere Verfasser: |
Chessel, Natacha,
Allioux, Clélia,
Marin, Pascale,
Piotton, Françoise,
Leuba, Geneviève,
Herrmann, François R,
Savioz, Armand |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2016
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Amyloid beta-Peptides
Peptide Fragments
amyloid beta-protein (1-40)
amyloid beta-protein (1-42)
Vitamin A
11103-57-4
Tretinoin
5688UTC01R |
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