Intravitreal Diclofenac in the Treatment of Macular Edema Due to Branch Retinal Vein Occlusion

Copyright 2016, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 47(2016), 2 vom: 11. Feb., Seite 149-55
1. Verfasser: Seth, Anisha (VerfasserIn)
Weitere Verfasser: Ghosh, Basudeb, Raina, Usha K, Gupta, Anika, Arora, Supriya
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Clinical Study Journal Article Anti-Inflammatory Agents, Non-Steroidal Ophthalmic Solutions Diclofenac 144O8QL0L1
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500 |a Citation Status MEDLINE 
520 |a Copyright 2016, SLACK Incorporated. 
520 |a BACKGROUND AND OBJECTIVE: To evaluate the effect of a single dose of intravitreal diclofenac on macular edema (ME) due to branch retinal vein occlusion (BRVO) 
520 |a PATIENTS AND METHODS: In this prospective, interventional case series, 15 eyes with BRVO and ME with central macular thickness (CMT) greater than 250 µm on spectral-domain optical coherence tomography (SD-OCT) were enrolled. All patients were given 0.05 mg/0.1 mL of intravitreal diclofenac under aseptic conditions and followed up for 3 months with respect to best-corrected visual acuity (BCVA), intraocular pressure (IOP), fundus fluorescein angiography, and CMT measured on OCT 
520 |a RESULTS: The mean visual acuity improved from 0.115 ± 0.03 preoperatively to 0.356 ± 0.29 at 3 months (P = .002). Mean line improvement was 2.2 ± 1.6. Mean preoperative CMT decreased from 453.2 µm ± 55.3 µm to 340.47 µm ± 101 µm at 3 months postoperatively (P = .001). The mean preoperative IOP was 16.4 mm Hg ± 1.59 mm Hg, whereas the mean postoperative IOP was 16.6 mm Hg ± 1.58 mm Hg (P = .08). None of the 12 phakic eyes showed evidence of cataract progression 
520 |a CONCLUSION: Intravitreal diclofenac is safe and effective in improving BCVA and decreasing CMT in patients with BRVO and ME 
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650 7 |a Ophthalmic Solutions  |2 NLM 
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700 1 |a Raina, Usha K  |e verfasserin  |4 aut 
700 1 |a Gupta, Anika  |e verfasserin  |4 aut 
700 1 |a Arora, Supriya  |e verfasserin  |4 aut 
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