Sarcocystid organisms found in bile from a dog with acute hepatitis a case report and review of intestinal and hepatobiliary Sarcocystidae infections in dogs and cats

Sarcocystid organisms found in bile from a dog with acute hepatitis : a case report and review of intestinal and hepatobiliary Sarcocystidae infections in dogs and cats

© 2016 American Society for Veterinary Clinical Pathology.

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 45(2016), 1 vom: 05. März, Seite 57-65
1. Verfasser: Irvine, Katherine L (VerfasserIn)
Weitere Verfasser: Walker, Julie M, Friedrichs, Kristen R
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Case Reports Journal Article Review Hammondia Neospora Sarcocystis Toxoplasma liver protozoan infections DNA, Ribosomal
Beschreibung
Zusammenfassung:© 2016 American Society for Veterinary Clinical Pathology.
Sarcocystidae is a family of coccidian protozoa from the phylum Apicomplexa that includes Toxoplasma, Neospora, Sarcocystis, Hammondia, and Besnoitia spp. All species undergo a 2-host sexual and asexual cycle. In the definitive host, replication is enteroepithelial, and infection is typically asymptomatic or less commonly causes mild diarrhea. Clinical disease is most frequently observed in the intermediate host, often as an aberrant infection, and is mostly associated with neurologic, muscular, or hepatic inflammation. Here, we review the literature regarding intestinal Sarcocystidae infections in dogs and cats, with emphasis on the life cycle stages and the available diagnostic assays and their limitations. We also report the diagnostic findings for an 11-year-old dog with acute neutrophilic hepatitis, biliary protozoa, and negative biliary culture. Although Toxoplasma and Neospora IgG titers were both high, PCR for these 2 organisms was negative for bile. The organisms were identified by 18S rDNA PCR as most consistent with Hammondia, either H heydorni or H triffittae. This is the first report of presumed Hammondia organisms being found in canine bile
Beschreibung:Date Completed 28.02.2018
Date Revised 28.02.2018
published: Print-Electronic
Citation Status MEDLINE
ISSN:1939-165X
DOI:10.1111/vcp.12330