Biomaterial-Enhanced Cell and Drug Delivery Lessons Learned in the Cardiac Field and Future Perspectives

Biomaterial-Enhanced Cell and Drug Delivery : Lessons Learned in the Cardiac Field and Future Perspectives

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 27 vom: 18. Juli, Seite 5648-61
1. Verfasser: O'Neill, Hugh S (VerfasserIn)
Weitere Verfasser: Gallagher, Laura B, O'Sullivan, Janice, Whyte, William, Curley, Clive, Dolan, Eimear, Hameed, Aamir, O'Dwyer, Joanne, Payne, Christina, O'Reilly, Daniel, Ruiz-Hernandez, Eduardo, Roche, Ellen T, O'Brien, Fergal J, Cryan, Sally Ann, Kelly, Helena, Murphy, Bruce, Duffy, Garry P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Review biomaterials cardiac tissue engineering drug delivery hydrogels stem cell therapy Biocompatible Materials
Beschreibung
Zusammenfassung:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Heart failure is a significant clinical issue. It is the cause of enormous healthcare costs worldwide and results in significant morbidity and mortality. Cardiac regenerative therapy has progressed considerably from clinical and preclinical studies delivering simple suspensions of cells, macromolecule, and small molecules to more advanced delivery methods utilizing biomaterial scaffolds as depots for localized targeted delivery to the damaged and ischemic myocardium. Here, regenerative strategies for cardiac tissue engineering with a focus on advanced delivery strategies and the use of multimodal therapeutic strategies are reviewed
Beschreibung:Date Completed 08.11.2018
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201505349