Molecular Insights into the Adsorption Mechanism of Human β-Defensin-3 on Bacterial Membranes

Human β-defensin-3 (hBD3) is an endogenous antimicrobial peptide that exhibits broad-spectrum antibacterial activity without eukaryotic cytotoxicity. In this work, we carried out molecular dynamics (MD) simulations to explore its adsorption mechanism on, and the structural and thermodynamic contribu...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 32(2016), 7 vom: 23. Feb., Seite 1782-90
Auteur principal: Lee, Juho (Auteur)
Autres auteurs: Jung, Sang Won, Cho, Art E
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't DEFB103A protein, human beta-Defensins