Photocrosslinking of Silk Fibroin Using Riboflavin for Ocular Prostheses

Photocrosslinking of Silk Fibroin Using Riboflavin for Ocular Prostheses

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Détails bibliographiques
Publié dans:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 12 vom: 23. März, Seite 2417-20
Auteur principal: Applegate, Matthew B (Auteur)
Autres auteurs: Partlow, Benjamin P, Coburn, Jeannine, Marelli, Benedetto, Pirie, Christopher, Pineda, Roberto, Kaplan, David L, Omenetto, Fiorenzo G
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Advanced materials (Deerfield Beach, Fla.)
Sujets:Journal Article Research Support, U.S. Gov't, Non-P.H.S. ocular prosthesis photocrosslinking silk Biocompatible Materials Fibroins 9007-76-5 Riboflavin TLM2976OFR
Description
Résumé:© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A novel method to photocrosslink silk fibroin protein is reported, using riboflavin (vitamin B2) as a photoinitiator and the mechanism of crosslinking is determined. Exposure of riboflavin-doped liquid silk solution to light results in the formation of a transparent, elastic hydrogel. Several applications for this new material are investigated including corneal reshaping to restore visual acuity and photolithography
Description:Date Completed 13.12.2016
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201504527