TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch

Histamine H4 receptor has been confirmed to play a role in evoking peripheral pruritus. However, the ionic and intracellular signaling mechanism of activation of H4 receptor on the dorsal root ganglion (DRG) neurons is still unknown. By using cell culture and calcium imaging, we studied the underlyi...

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Veröffentlicht in:Neural plasticity. - 1998. - 2016(2016) vom: 01., Seite 1682972
1. Verfasser: Jian, Tunyu (VerfasserIn)
Weitere Verfasser: Yang, Niuniu, Yang, Yan, Zhu, Chan, Yuan, Xiaolin, Yu, Guang, Wang, Changming, Wang, Zhongli, Shi, Hao, Tang, Min, He, Qian, Lan, Lei, Wu, Guanyi, Tang, Zongxiang
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide Acetanilides Acrylamides Antipruritics Bridged Bicyclo Compounds, Heterocyclic Histamine Agonists Hrh4 protein, mouse mehr... Imidazoles Piperidines Purines Receptors, G-Protein-Coupled Receptors, Histamine Receptors, Histamine H4 TRPV Cation Channels TRPV1 protein, mouse 4-(1H-imidazol-4-ylmethyl)piperidine 151070-83-6 Type C Phospholipases EC 3.1.4.- Capsaicin S07O44R1ZM Calcium SY7Q814VUP