Nanoscale Engineering of Designer Cellulosomes

© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 27 vom: 30. Juli, Seite 5619-47
1. Verfasser: Gunnoo, Melissabye (VerfasserIn)
Weitere Verfasser: Cazade, Pierre-André, Galera-Prat, Albert, Nash, Michael A, Czjzek, Mirjam, Cieplak, Marek, Alvarez, Beatriz, Aguilar, Marina, Karpol, Alon, Gaub, Hermann, Carrión-Vázquez, Mariano, Bayer, Edward A, Thompson, Damien
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article materials modeling molecular dynamics calculations nanobiomaterials protein re-engineering renewable energy
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520 |a Biocatalysts showcase the upper limit obtainable for high-speed molecular processing and transformation. Efforts to engineer functionality in synthetic nanostructured materials are guided by the increasing knowledge of evolving architectures, which enable controlled molecular motion and precise molecular recognition. The cellulosome is a biological nanomachine, which, as a fundamental component of the plant-digestion machinery from bacterial cells, has a key potential role in the successful development of environmentally-friendly processes to produce biofuels and fine chemicals from the breakdown of biomass waste. Here, the progress toward so-called "designer cellulosomes", which provide an elegant alternative to enzyme cocktails for lignocellulose breakdown, is reviewed. Particular attention is paid to rational design via computational modeling coupled with nanoscale characterization and engineering tools. Remaining challenges and potential routes to industrial application are put forward 
650 4 |a Journal Article 
650 4 |a materials modeling 
650 4 |a molecular dynamics calculations 
650 4 |a nanobiomaterials 
650 4 |a protein re-engineering 
650 4 |a renewable energy 
700 1 |a Cazade, Pierre-André  |e verfasserin  |4 aut 
700 1 |a Galera-Prat, Albert  |e verfasserin  |4 aut 
700 1 |a Nash, Michael A  |e verfasserin  |4 aut 
700 1 |a Czjzek, Mirjam  |e verfasserin  |4 aut 
700 1 |a Cieplak, Marek  |e verfasserin  |4 aut 
700 1 |a Alvarez, Beatriz  |e verfasserin  |4 aut 
700 1 |a Aguilar, Marina  |e verfasserin  |4 aut 
700 1 |a Karpol, Alon  |e verfasserin  |4 aut 
700 1 |a Gaub, Hermann  |e verfasserin  |4 aut 
700 1 |a Carrión-Vázquez, Mariano  |e verfasserin  |4 aut 
700 1 |a Bayer, Edward A  |e verfasserin  |4 aut 
700 1 |a Thompson, Damien  |e verfasserin  |4 aut 
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