Huperzine A Alleviates Mechanical Allodynia but Not Spontaneous Pain via Muscarinic Acetylcholine Receptors in Mice

Chronic pain is a major health issue and most patients suffer from spontaneous pain. Previous studies suggest that Huperzine A (Hup A), an alkaloid isolated from the Chinese herb Huperzia serrata, is a potent analgesic with few side effects. However, whether it alleviates spontaneous pain is unclear...

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Bibliographische Detailangaben
Veröffentlicht in:Neural plasticity. - 1998. - 2015(2015) vom: 03., Seite 453170
1. Verfasser: Zuo, Zhen-Xing (VerfasserIn)
Weitere Verfasser: Wang, Yong-Jie, Liu, Li, Wang, Yiner, Mei, Shu-Hao, Feng, Zhi-Hui, Wang, Maode, Li, Xiang-Yao
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Alkaloids Analgesics Cholinesterase Inhibitors Lipopolysaccharides Muscarinic Antagonists Receptors, Muscarinic Sesquiterpenes huperzine A mehr... 0111871I23 Ambenonium Chloride 51FOB87G3I Atropine 7C0697DR9I Acetylcholinesterase EC 3.1.1.7 Clonidine MN3L5RMN02