Efficient Condensation of DNA into Environmentally Responsive Polyplexes Produced from Block Catiomers Carrying Amine or Diamine Groups

The intracellular delivery of nucleic acids requires a vector system as they cannot diffuse across lipid membranes. Although polymeric transfecting agents have been extensively investigated, none of the proposed gene delivery vehicles fulfill all of the requirements needed for an effective therapy,...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 32(2016), 2 vom: 19. Jan., Seite 577-86
1. Verfasser: Albuquerque, Lindomar J C (VerfasserIn)
Weitere Verfasser: Annes, Kelly, Milazzotto, Marcella P, Mattei, Bruno, Riske, Karin A, Jäger, Eliézer, Pánek, Jiří, Štěpánek, Petr, Kapusta, Peter, Muraro, Paulo I R, De Freitas, Augusto G O, Schmidt, Vanessa, Giacomelli, Cristiano, Bonvent, Jean-Jacques, Giacomelli, Fernando C
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Methacrylates Polymethacrylic Acids poly(2-(diisopropylamino)ethyl methacrylate) polyethylene glycol methacrylate Polyethylene Glycols 3WJQ0SDW1A DNA 9007-49-2