New insights on single-stranded versus double-stranded DNA library preparation for ancient DNA

An innovative single-stranded DNA (ssDNA) library preparation method has sparked great interest among ancient DNA (aDNA) researchers, especially after reports of endogenous DNA content increases >20-fold in some samples. To investigate the behavior of this method, we generated ssDNA and conventio...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1993. - 59(2015), 6 vom: 18. Dez., Seite 368-71
1. Verfasser: Wales, Nathan (VerfasserIn)
Weitere Verfasser: Carøe, Christian, Sandoval-Velasco, Marcela, Gamba, Cristina, Barnett, Ross, Samaniego, José Alfredo, Madrigal, Jazmín Ramos, Orlando, Ludovic, Gilbert, M Thomas P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, Non-U.S. Gov't DNA library preparation ancient DNA next-generation sequencing paleogenomics DNA, Single-Stranded DNA 9007-49-2