First Evidence of the Liposome-Mediated Deintercalation of Anticancer Drug Doxorubicin from the Drug-DNA Complex : A Spectroscopic Approach

Biocompatible liposomes were used for the first time to study the deintercalation process of a prominent anticancer drug, doxorubicin (DOX), from doxorubicin-intercalated DNA (DOX-DNA complex) under controlled experimental conditions. The study revealed that anionic liposomes (DMPG liposomes) appear...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 32(2016), 1 vom: 12. Jan., Seite 159-70
Auteur principal: Das, Anupam (Auteur)
Autres auteurs: Adhikari, Chandan, Nayak, Debasis, Chakraborty, Anjan
Format: Article en ligne
Langue:English
Publié: 2016
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents DNA Adducts Liposomes doxorubicin-DNA Doxorubicin 80168379AG