Alterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor Fluoxetine

Ceramides induce important intracellular signaling pathways, modulating proliferation, migration, apoptosis, and inflammation. However, the relevance of the ceramide metabolism in the reconvalescence phase after stroke is unclear. Besides its well-known property as a selective serotonin reuptake inh...

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Veröffentlicht in:Neural plasticity. - 1998. - 2015(2015) vom: 30., Seite 503079
1. Verfasser: Brunkhorst, R (VerfasserIn)
Weitere Verfasser: Friedlaender, F, Ferreirós, N, Schwalm, S, Koch, A, Grammatikos, G, Toennes, S, Foerch, C, Pfeilschifter, J, Pfeilschifter, W
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Ceramides Enzyme Inhibitors Serotonin Uptake Inhibitors Fluoxetine 01K63SUP8D Sphingomyelin Phosphodiesterase EC 3.1.4.12