Degradable Magnetic Composites for Minimally Invasive Interventions Device Fabrication, Targeted Drug Delivery, and Cytotoxicity Tests

Degradable Magnetic Composites for Minimally Invasive Interventions : Device Fabrication, Targeted Drug Delivery, and Cytotoxicity Tests

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 3 vom: 20. Jan., Seite 533-8
1. Verfasser: Peters, Christian (VerfasserIn)
Weitere Verfasser: Hoop, Marcus, Pané, Salvador, Nelson, Bradley J, Hierold, Christofer
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't cytotoxicity degradable composites superparamagnetic particles swimming microrobots targeted drug delivery Acrylates Drug Carriers Propylene Glycols mehr... poly(ethylene glycol)diacrylate Polyethylene Glycols 3WJQ0SDW1A pentaerythrityl triacrylate PJJ1161ULF
Beschreibung
Zusammenfassung:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Superparamagnetic nanoparticles and a functional, degradable polymer matrix based on poly(ethylene glycol) are combined to enable fully degradable magnetic microdevices for minimally invasive biomedical applications. A bioinspired helical microrobot platform mimicking Escherichia coli bacteria is fabricated and actuated using weak rotating magnetic fields. Locomotion based on corkscrew propulsion, targeted drug delivery, and low-degradation-product cytotoxicity are demonstrated
Beschreibung:Date Completed 12.10.2016
Date Revised 08.01.2021
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201503112