Effect of a c-MYC Gene Polymorphism (g.3350G>C) on Meat Quality Traits in Berkshire

c-MYC (v-myelocytomatosis viral oncogene homologue) is a transcription factor that plays important role in many biological process including cell growth and differentiation, such as myogenesis and adipogenesis. In this study, we aimed to detect MYC gene polymorphisms, their genotype frequencies and...

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Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 28(2015), 11 vom: 13. Nov., Seite 1545-50
1. Verfasser: Oh, J D (VerfasserIn)
Weitere Verfasser: Kim, E S, Lee, H K, Song, K D
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article Association Analysis Berkshire Meat Quality Traits Single Nucleotide Polymorphism v-Myelocytomatosis Viral Oncogene Homologue
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520 |a c-MYC (v-myelocytomatosis viral oncogene homologue) is a transcription factor that plays important role in many biological process including cell growth and differentiation, such as myogenesis and adipogenesis. In this study, we aimed to detect MYC gene polymorphisms, their genotype frequencies and to determine associations between these polymorphisms and meat quality traits in Berkshire pigs. We identified a single nucleotide polymorphism (SNP) in intron 2 of MYC gene by Sanger sequencing, i.e., g.3350G>C (rs321898326), that is only found in Berkshire pigs, but not in other breeds including Duroc, Landrace, and Yorkshire pigs that were used in this study. Genotypes of total 378 Berkshire pigs (138 sows and 240 boars) were determined using Hha I restriction enzyme digestion after polymerase chain reaction. Observed allele frequencies of GG, GC, and CC genotypes were 0.399, 0.508, and 0.093 respectively. Statistical analysis indicated that the g.3350G>C polymorphism was significantly associated with pH45min and cooking loss (p<0.05), suggesting that g.3350G>C SNP can be used for pre-selection of pH45min and cooking loss traits in Berkshire pigs 
650 4 |a Journal Article 
650 4 |a Association Analysis 
650 4 |a Berkshire 
650 4 |a Meat Quality Traits 
650 4 |a Single Nucleotide Polymorphism 
650 4 |a v-Myelocytomatosis Viral Oncogene Homologue 
700 1 |a Kim, E S  |e verfasserin  |4 aut 
700 1 |a Lee, H K  |e verfasserin  |4 aut 
700 1 |a Song, K D  |e verfasserin  |4 aut 
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