Multifunctional Silica Nanoparticles for Covalent Immobilization of Highly Sensitive Proteins

Multifunctional Silica Nanoparticles for Covalent Immobilization of Highly Sensitive Proteins

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 48 vom: 22. Dez., Seite 7945-50
1. Verfasser: Wang, Xu-Dong (VerfasserIn)
Weitere Verfasser: Rabe, Kersten S, Ahmed, Ishtiaq, Niemeyer, Christof M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't biomolecules immobilization proteins silica nanoparticles surface chemistry Immobilized Proteins Sulfhydryl Compounds Silicon Dioxide mehr... 7631-86-9 Glucose IY9XDZ35W2
Beschreibung
Zusammenfassung:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A convenient reverse micellar one-pot reaction yields multifunctional silica nanoparticles, which can be tailored to effectively suppress non-specific adsorption and, at the same time, enable efficient specific covalent immobilization of proteins. Using two highly sensitive proteins, it is demonstrated that the new particles provide a suitable microenvironment to maintain the protein's activity
Beschreibung:Date Completed 12.10.2016
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201503935