A Near-Infrared Laser-Activated "Nanobomb" for Breaking the Barriers to MicroRNA Delivery

A Near-Infrared Laser-Activated "Nanobomb" for Breaking the Barriers to MicroRNA Delivery

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 2 vom: 13. Jan., Seite 347-55
1. Verfasser: Wang, Hai (VerfasserIn)
Weitere Verfasser: Agarwal, Pranay, Zhao, Shuting, Yu, Jianhua, Lu, Xiongbin, He, Xiaoming
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't cancer stem-like cells endosomal escape gene delivery microRNAs nanoparticles Hyaluronan Receptors MicroRNAs
Beschreibung
Zusammenfassung:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A near-infrared laser-activated "nanobomb" is synthesized using lipid and multiple polymers to break the extra-cellular and intracellular barriers to cytosolic delivery of microRNAs. The nanobomb can be used to effectively destroy tumors and cancer stem-like cells in vitro and in vivo with minimal side effects
Beschreibung:Date Completed 15.12.2016
Date Revised 30.09.2020
published: Print-Electronic
ErratumIn: Adv Mater. 2016 Mar;28(9):1723. - PMID 26928112
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201504263