The Combination Therapy of Gemcitabine Plus Paclitaxel Induced Complete Response in a Tongue Skin Brain Metastasis of Bladder Carcinoma A Case Report

The Combination Therapy of Gemcitabine Plus Paclitaxel Induced Complete Response in a Tongue Skin Brain Metastasis of Bladder Carcinoma : A Case Report

Tongue, skin and brain metastases of bladder cancer are very rare and few cases have been reported. We report a case of tongue, skin and brain metastases of bladder cancer. A 61-year-old woman was referred to our hospital with gross hematuria. Transurethral resection of the bladder (TURBT), tongue b...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 61(2015), 10 vom: 15. Okt., Seite 405-9
1. Verfasser: Uemura, Yuichi (VerfasserIn)
Weitere Verfasser: Ushida, Hiroshi, Ishitoya, Satoshi, Onishi, Hiroyuki, Terashima, Tsuyoshi, Takeuchi, Eiji
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports English Abstract Journal Article Deoxycytidine 0W860991D6 Paclitaxel P88XT4IS4D Gemcitabine
Beschreibung
Zusammenfassung:Tongue, skin and brain metastases of bladder cancer are very rare and few cases have been reported. We report a case of tongue, skin and brain metastases of bladder cancer. A 61-year-old woman was referred to our hospital with gross hematuria. Transurethral resection of the bladder (TURBT), tongue biopsy and skin biopsy were performed. Pathological findings showed urothelial carcinoma, G2, micro papillary variant, pT2＞ and tongue and skin metastases from urothelial carcinoma of bladder. After three cycles of chemotherapy (gemcitabine plus paclitaxel), tongue and skin metastases disappeared. Cystoscopy revealed no tumor of bladder. Eleven months later, she was admitted to our hospital because of disturbance of consciousness. Magnetic resonance imaging (MRI) showed multiple brain metastases. Rechallenge of chemotherapy (gemcitabine plus paclitaxel) restored from disturbance of consciousness and MRI showed partial response of brain metastases. We performed six additional courses of chemotherapy. Skin, tongue and brain metastases from bladder cancer indicate poor risk. Chemotherapy (gemcitabine plus paclitaxel)could be effective against these matastases
Beschreibung:Date Completed 25.04.2016
Date Revised 07.12.2022
published: Print
Citation Status MEDLINE
ISSN:0018-1994