A Bio-Acoustic Levitational (BAL) Assembly Method for Engineering of Multilayered, 3D Brain-Like Constructs, Using Human Embryonic Stem Cell Derived Neuro-Progenitors
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publié dans: | Advanced materials (Deerfield Beach, Fla.). - 1998. - 28(2016), 1 vom: 06. Jan., Seite 161-7 |
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Auteur principal: | |
Autres auteurs: | , , , , , |
Format: | Article en ligne |
Langue: | English |
Publié: |
2016
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Accès à la collection: | Advanced materials (Deerfield Beach, Fla.) |
Sujets: | Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. bulk acoustic standing waves multilayered 3D tissue structures neural constructs neural progenitor cells tissue engineering |
Résumé: | © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. A bio-acoustic levitational assembly method for engineering of multilayered, 3D brainlike constructs is presented. Acoustic radiation forces are used to levitate neuroprogenitors derived from human embryonic stem cells in 3D multilayered fibrin tissue constructs. The neuro-progenitor cells are subsequently differentiated in neural cells, resulting in a 3D neuronal construct with inter and intralayer neurite elongations |
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Description: | Date Completed 12.10.2016 Date Revised 30.09.2020 published: Print-Electronic Citation Status MEDLINE |
ISSN: | 1521-4095 |
DOI: | 10.1002/adma.201503916 |