Development of a novel hepatitis B virus encapsidation detection assay by viral nucleocapsid-captured quantitative RT-PCR
After encapsidation, where pregenomic RNA (pgRNA) is packaged into viral nucleocapsids, hepatitis B virus (HBV) uses the pgRNA as a template to replicate its DNA genome by reverse transcription. To date, there are only two encapsidation detection methods for evaluating the amount of pgRNA packaged i...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | BioTechniques. - 1991. - 59(2015), 5 vom: 15. Nov., Seite 287-93
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1. Verfasser: |
Ryu, Dong-Kyun
(VerfasserIn) |
Weitere Verfasser: |
Ahn, Yeji,
Ryu, Wang-Shick,
Windisch, Marc P |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2015
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Zugriff auf das übergeordnete Werk: | BioTechniques
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Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
antiviral assay
encapsidation
hepatitis B virus
pregenomic RNA
RNA, Viral |