Growth inhibition and possible mechanism of oleamide against the toxin-producing cyanobacterium Microcystis aeruginosa NIES-843

Oleamide, a fatty acid derivative, shows inhibitory effect against the bloom-forming cyanobacterium Microcystis aeruginosa. The EC50 of oleamide on the growth of M. aeruginosa NIES-843 was 8.60 ± 1.20 mg/L. In order to elucidate the possible mechanism of toxicity of oleamide against M. aeruginosa, c...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 25(2016), 1 vom: 07. Jan., Seite 225-33
1. Verfasser: Shao, Jihai (VerfasserIn)
Weitere Verfasser: He, Yaxian, Li, Fan, Zhang, Huiling, Chen, Anwei, Luo, Si, Gu, Ji-Dong
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Growth inhibition Microcystins Microcystis aeruginosa Oleamide Photosynthesis Oleic Acids Photosystem II Protein Complex oleylamide 7L25QK8BWO
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520 |a Oleamide, a fatty acid derivative, shows inhibitory effect against the bloom-forming cyanobacterium Microcystis aeruginosa. The EC50 of oleamide on the growth of M. aeruginosa NIES-843 was 8.60 ± 1.20 mg/L. In order to elucidate the possible mechanism of toxicity of oleamide against M. aeruginosa, chlorophyll fluorescence transient, cellular ultrastructure, fatty acids composition and the transcription of the mcyB gene involved in microcystins synthesis were studied. The results of chlorophyll fluorescence transient showed that oleamide could destruct the electron accepting side of the photosystem II of M. aeruginosa NIES-843. Cellular ultrastructure examination indicated that the destruction of fatty acid constituents, the distortion of thylakoid membrane and the loss of integrity of cell membrane were associated with oleamide treatment and concentration. The damage of cellular membrane increased the release of microcystins from intact cells into the medium. Results presented in this study provide new information on the possible mechanisms involved and potential utilization of oleamide as an algicide in cyanobacterial bloom control 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Growth inhibition 
650 4 |a Microcystins 
650 4 |a Microcystis aeruginosa 
650 4 |a Oleamide 
650 4 |a Photosynthesis 
650 7 |a Microcystins  |2 NLM 
650 7 |a Oleic Acids  |2 NLM 
650 7 |a Photosystem II Protein Complex  |2 NLM 
650 7 |a oleylamide  |2 NLM 
650 7 |a 7L25QK8BWO  |2 NLM 
700 1 |a He, Yaxian  |e verfasserin  |4 aut 
700 1 |a Li, Fan  |e verfasserin  |4 aut 
700 1 |a Zhang, Huiling  |e verfasserin  |4 aut 
700 1 |a Chen, Anwei  |e verfasserin  |4 aut 
700 1 |a Luo, Si  |e verfasserin  |4 aut 
700 1 |a Gu, Ji-Dong  |e verfasserin  |4 aut 
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