A Simple Low-dose X-ray CT Simulation from High-dose Scan

Low-dose X-ray computed tomography (CT) simulation from high-dose scan is required in optimizing radiation dose to patients. In this study, we propose a simple low-dose CT simulation strategy in sinogram domain using the raw data from high-dose scan. Specially, a relationship between the incident fl...

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Publié dans:IEEE transactions on nuclear science. - 1988. - 62(2015), 5 vom: 01. Okt., Seite 2226-2233
Auteur principal: Zeng, Dong (Auteur)
Autres auteurs: Huang, Jing, Bian, Zhaoying, Niu, Shanzhou, Zhang, Hua, Feng, Qianjin, Liang, Zhengrong, Ma, Jianhua
Format: Article
Langue:English
Publié: 2015
Accès à la collection:IEEE transactions on nuclear science
Sujets:Journal Article X-ray CT high-dose low-dose simulation
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520 |a Low-dose X-ray computed tomography (CT) simulation from high-dose scan is required in optimizing radiation dose to patients. In this study, we propose a simple low-dose CT simulation strategy in sinogram domain using the raw data from high-dose scan. Specially, a relationship between the incident fluxes of low- and high- dose scans is first determined according to the repeated projection measurements and analysis. Second, the incident flux level of the simulated low-dose scan is generated by properly scaling the incident flux level of high-dose scan via the determined relationship in the first step. Third, the low-dose CT transmission data by energy integrating detection is simulated by adding a statistically independent Poisson noise distribution plus a statistically independent Gaussian noise distribution. Finally, a filtered back-projection (FBP) algorithm is implemented to reconstruct the resultant low-dose CT images. The present low-dose simulation strategy is verified on the simulations and real scans by comparing it with the existing low-dose CT simulation tool. Experimental results demonstrated that the present low-dose CT simulation strategy can generate accurate low-dose CT sinogram data from high-dose scan in terms of qualitative and quantitative measurements 
650 4 |a Journal Article 
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700 1 |a Huang, Jing  |e verfasserin  |4 aut 
700 1 |a Bian, Zhaoying  |e verfasserin  |4 aut 
700 1 |a Niu, Shanzhou  |e verfasserin  |4 aut 
700 1 |a Zhang, Hua  |e verfasserin  |4 aut 
700 1 |a Feng, Qianjin  |e verfasserin  |4 aut 
700 1 |a Liang, Zhengrong  |e verfasserin  |4 aut 
700 1 |a Ma, Jianhua  |e verfasserin  |4 aut 
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