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231224s2015 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.5b03291
|2 doi
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|a pubmed24n0847.xml
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|a DE-627
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|a eng
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|a Xia, Yan
|e verfasserin
|4 aut
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|a Effects of Nanoparticle Morphology and Acyl Chain Length on Spontaneous Lipid Transfer Rates
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|c 2015
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|a Text
|b txt
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|a ƒaComputermedien
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|a Date Completed 16.09.2016
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|a Date Revised 01.12.2015
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a We report on studies of lipid transfer rates between different morphology nanoparticles and lipids with different length acyl chains. The lipid transfer rate of dimyristoylphosphatidylcholine (di-C14, DMPC) in discoidal "bicelles" (0.156 h(-1)) is 2 orders of magnitude greater than that of DMPC vesicles (ULVs) (1.1 × 10(-3) h(-1)). For both bicellar and ULV morphologies, increasing the acyl chain length by two carbons [going from di-C14 DMPC to di-C16, dipalmitoylphosphatidylcholine (DPPC)] causes lipid transfer rates to decrease by more than 2 orders of magnitude. Results from small angle neutron scattering (SANS), differential scanning calorimetry (DSC), and fluorescence correlation spectroscopy (FCS) are in good agreement. The present studies highlight the importance of lipid dynamic processes taking place in different morphology biomimetic membranes
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|a Journal Article
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|a Research Support, U.S. Gov't, Non-P.H.S.
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|a 1,2-Dipalmitoylphosphatidylcholine
|2 NLM
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|a 2644-64-6
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|a Dimyristoylphosphatidylcholine
|2 NLM
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|a U86ZGC74V5
|2 NLM
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|a Li, Ming
|e verfasserin
|4 aut
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|a Charubin, Kamil
|e verfasserin
|4 aut
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|a Liu, Ying
|e verfasserin
|4 aut
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|a Heberle, Frederick A
|e verfasserin
|4 aut
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|a Katsaras, John
|e verfasserin
|4 aut
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|a Jing, Benxin
|e verfasserin
|4 aut
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|a Zhu, Yingxi
|e verfasserin
|4 aut
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|a Nieh, Mu-Ping
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 31(2015), 47 vom: 01. Dez., Seite 12920-8
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|g volume:31
|g year:2015
|g number:47
|g day:01
|g month:12
|g pages:12920-8
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|u http://dx.doi.org/10.1021/acs.langmuir.5b03291
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