Compact CT/SPECT Small-Animal Imaging System
We have developed a dual-modality CT/SPECT imaging system for small-animal imaging applications. The X-ray system comprises a commercially available micro-focus X-ray tube and a CCD-based X-ray camera. X-ray transmission measurements are performed based on cone-beam geometry. Individual projections...
| Veröffentlicht in: | IEEE transactions on nuclear science. - 1988. - 51(2004), 1 vom: 01. Feb., Seite 63-67 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2004
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| Zugriff auf das übergeordnete Werk: | IEEE transactions on nuclear science |
| Schlagworte: | Journal Article Biomedical imaging cadmium zinc telluride (CdZnTe) multimodality imaging single-photon emission computed tomography small-animal imaging |
| Zusammenfassung: | We have developed a dual-modality CT/SPECT imaging system for small-animal imaging applications. The X-ray system comprises a commercially available micro-focus X-ray tube and a CCD-based X-ray camera. X-ray transmission measurements are performed based on cone-beam geometry. Individual projections are acquired by rotating the animal about a vertical axis in front of the CCD detector. A high-resolution CT image is obtained after reconstruction using an ordered subsets-expectation maximization (OS-EM) reconstruction algorithm. The SPECT system utilizes a compact semiconductor camera module previously developed in our group. The module is mounted perpendicular to the X-ray tube/CCD combination. It consists of a 64×64 pixellated CdZnTe detector and a parallel-hole tungsten collimator. The field of view is 1 square inch. Planar projections for SPECT reconstruction are obtained by rotating the animal in front of the detector. Gamma-ray and X-ray images are presented of phantoms and mice. Procedures for merging the anatomical and functional images are discussed |
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| Beschreibung: | Date Revised 20.11.2019 published: Print Citation Status Publisher |
| ISSN: | 0018-9499 |