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231224s2015 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201502865
|2 doi
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|a pubmed24n0843.xml
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|a eng
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| 100 |
1 |
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|a Guo, Xing
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Size Changeable Nanocarriers with Nuclear Targeting for Effectively Overcoming Multidrug Resistance in Cancer Therapy
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| 264 |
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|c 2015
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|a Text
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|a ƒaComputermedien
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|a Date Completed 01.11.2016
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a A size changeable polymer micelle system with a dual shell, which increases in size under acidic pH conditions and is altered to smaller micelles, triggered by intracellular glutathione (GSH), is successfully developed. It is capable of direct delivering anticancer drugs to the nucleus of multidrug resistance (MDR) tumor cells for highly effective combating of drug resistant breast cancer
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a cancer therapy
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|a multidrug resistance
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|a nanocarriers
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|a nuclear targeting
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|a reductive-sensitive materials
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|a Antineoplastic Agents
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|a Drug Carriers
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| 650 |
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7 |
|a Micelles
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|a Polymers
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| 650 |
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|a Doxorubicin
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|a Jing, Yuting
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|a Zhou, Shaobing
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|t Advanced materials (Deerfield Beach, Fla.)
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|g 27(2015), 41 vom: 04. Nov., Seite 6450-6
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