A Prussian Blue-Based Core-Shell Hollow-Structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH-Responsive Longitudinal Relaxivity

A Prussian Blue-Based Core-Shell Hollow-Structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH-Responsive Longitudinal Relaxivity

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 41 vom: 04. Nov., Seite 6382-9
1. Verfasser: Cai, Xiaojun (VerfasserIn)
Weitere Verfasser: Gao, Wei, Ma, Ming, Wu, Meiying, Zhang, Linlin, Zheng, Yuanyi, Chen, Hangrong, Shi, Jianlin
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Prussian blue magnetic resonance imaging manganese pH-responsive theranostics Antineoplastic Agents Contrast Media Drug Carriers mehr... Ferrocyanides Manganese Compounds Oxides RNA, Small Interfering manganese oxide 64J2OA7MH3 Silicon Dioxide 7631-86-9 Doxorubicin 80168379AG ferric ferrocyanide TLE294X33A
Beschreibung
Zusammenfassung:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Novel core-shell hollow mesoporous Prussian blue Mn-containing Prussian blue analogue (HMPB@MnPBA) nanoparticles, designated as HMPB-Mn) as an intelligent theranostic nanoagent, are successfully constructed by coating a similarly crystal-structured MnPBA onto HMPB. This can be used as a pH-responsive T1 -weighted magnetic resonance imaging contrast agent with ultrahigh longitudinal relaxivity (r1 = 7.43 m m(-1) s(-1) ), and achieves the real-time monitoring of drug release
Beschreibung:Date Completed 01.11.2016
Date Revised 31.03.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201503381