Transient cold agglutinins associated with Mycoplasma cynos pneumonia in a dog

© 2015 American Society for Veterinary Clinical Pathology.

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 44(2015), 4 vom: 26. Dez., Seite 498-502
1. Verfasser: Pinkos, Alyssa C (VerfasserIn)
Weitere Verfasser: Friedrichs, Kristen R, Monaghan, Kelly N, Sample, Saundra H, Trepanier, Lauren A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Case Reports Journal Article Agglutination erythrocyte agglutination test pulmonary infection red blood cell saline dilution Anti-Bacterial Agents Fluoroquinolones Enrofloxacin 3DX3XEK1BN
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520 |a This report details a case of reversible cold agglutinins in a dog with Mycoplasma cynos pneumonia. An 11-month-old female spayed Rhodesian Ridgeback was presented for lethargy and cough. Thoracic radiographs revealed an alveolar pattern present bilaterally in the cranioventral lung lobes. Septic neutrophilic inflammation with suspected Mycoplasma sp. organisms was noted on cytologic examination of a trans-tracheal wash, and the dog was treated empirically with IV ampicillin/sulbactam and enrofloxacin pending culture results. Red blood cell agglutination was noted unexpectedly on several blood film reviews during hospitalization; however, the dog never developed clinical or laboratory evidence of hemolysis. Cold agglutinins were demonstrated based on the results of a saline dilution and cold agglutinin test that showed agglutination at 4°C but not at room temperature (21°C) or 37°C. Based on a positive culture for M cynos, the dog was treated for 8 weeks with oral enrofloxacin. After clinical and radiographic resolution of the pneumonia, repeated saline dilution and cold agglutinin tests of peripheral blood were negative at all temperatures. Reversible, asymptomatic cold agglutinins are common in human patients with mycoplasma pneumonia, but this is the first reported case in a dog 
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650 4 |a Agglutination 
650 4 |a erythrocyte agglutination test 
650 4 |a pulmonary infection 
650 4 |a red blood cell 
650 4 |a saline dilution 
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650 7 |a Fluoroquinolones  |2 NLM 
650 7 |a Enrofloxacin  |2 NLM 
650 7 |a 3DX3XEK1BN  |2 NLM 
700 1 |a Friedrichs, Kristen R  |e verfasserin  |4 aut 
700 1 |a Monaghan, Kelly N  |e verfasserin  |4 aut 
700 1 |a Sample, Saundra H  |e verfasserin  |4 aut 
700 1 |a Trepanier, Lauren A  |e verfasserin  |4 aut 
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