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231224s2015 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201502598
|2 doi
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|a pubmed24n0841.xml
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|a eng
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| 100 |
1 |
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|a Zhang, Di
|e verfasserin
|4 aut
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| 245 |
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|a In Situ Formation of Nanofibers from Purpurin18-Peptide Conjugates and the Assembly Induced Retention Effect in Tumor Sites
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|c 2015
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 04.08.2016
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a An assembly-induced retention effect for enhanced tumor photoacoustic (PA) imaging and therapeutics is described. A responsive small-molecule precursor is prepared that simultaneously self-assembles into nanofibers in tumor sites that exhibit an assembly-induced retention effect, which results in an improved PA imaging signal and enhanced therapeutic efficacy. This successful proof-of-concept study paves the way to develop novel supramolecular biomaterials for cancer diagnostics and therapeutics
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a chlorophyll
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|a nanomaterials
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|a photoacoustic imaging
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4 |
|a supramolecular structures
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4 |
|a tumor therapies
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| 650 |
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7 |
|a Antineoplastic Agents
|2 NLM
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| 650 |
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|a Porphyrins
|2 NLM
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| 650 |
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|a purpurin 18
|2 NLM
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| 650 |
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|a 25465-77-4
|2 NLM
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| 650 |
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|a Etoposide
|2 NLM
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|a Gelatinases
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|2 NLM
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| 700 |
1 |
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|a Qi, Guo-Bin
|e verfasserin
|4 aut
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1 |
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|a Zhao, Ying-Xi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Qiao, Sheng-Lin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yang, Chao
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Hao
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 27(2015), 40 vom: 28. Okt., Seite 6125-30
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