Role of translocated bacterial flagellin in monocyte activation among individuals with chronic HIV-1 infection

Monocyte activation has been identified as a predictor of mortality and morbidity in HIV-1 infection. This study investigated translocated bacterial flagellin as a potential contributor to systemic monocyte activation via Toll-like receptor 5 (TLR5) stimulation.We demonstrated that circulating flage...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 161(2015), 2 vom: 01. Dez., Seite 180-9
1. Verfasser: Svärd, Jenny (VerfasserIn)
Weitere Verfasser: Paquin-Proulx, Dominic, Buggert, Marcus, Noyan, Kajsa, Barqasho, Babilonia, Sönnerborg, Anders, Nowak, Piotr
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Flagellin HIV-1 Lipopolysaccharide (LPS) Microbial translocation Monocyte activation Toll-like receptor 5 Interleukins Lipopolysaccharides mehr... TLR5 protein, human Toll-Like Receptor 5 12777-81-0