Altered B-cell subsets and functional B-cell defects in selective IgM deficiency
Primary selective IgM deficiency (sIgM) is characterized by diminished serum IgM, infections and autoimmunity. Although there is some evidence of B-cell defects the pathogenesis of sIgM is poorly understood. We determined peripheral B-cell subsets and IgM-expression levels in 31 adult sIgM patients...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 161(2015), 2 vom: 08. Dez., Seite 96-102
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| 1. Verfasser: |
Mensen, Angela
(VerfasserIn) |
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| Weitere Verfasser: |
Krause, Torben,
Hanitsch, Leif Gunnar,
Meisel, Christian,
Kleint, Maximilian E,
Volk, Hans-Dieter,
Na, Il-Kang,
Scheibenbogen, Carmen |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2015
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Antibody-secreting cells
ELISpot assay
Memory B cells
Primary immunodeficiency
Selective IgM deficiency
Transitional B cells
Antibodies
Immunoglobulin M |
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