|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM252401379 |
| 003 |
DE-627 |
| 005 |
20250219021532.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2015 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.5713/ajas.14.0696
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0841.xml
|
| 035 |
|
|
|a (DE-627)NLM252401379
|
| 035 |
|
|
|a (NLM)26333666
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Moon, Sunjin
|e verfasserin
|4 aut
|
| 245 |
1 |
2 |
|a A Genome-wide Scan for Selective Sweeps in Racing Horses
|
| 264 |
|
1 |
|c 2015
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 20.11.2015
|
| 500 |
|
|
|a Date Revised 18.03.2022
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status PubMed-not-MEDLINE
|
| 520 |
|
|
|a Using next-generation sequencing, we conducted a genome-wide scan of selective sweeps associated with selection toward genetic improvement in Thoroughbreds. We investigated potential phenotypic consequence of putative candidate loci by candidate gene association mapping for the finishing time in 240 Thoroughbred horses. We found a significant association with the trait for Ral GApase alpha 2 (RALGAP2) that regulates a variety of cellular processes of signal trafficking. Neighboring genes around RALGAP2 included insulinoma-associated 1 (INSM1), pallid (PLDN), and Ras and Rab interactor 2 (RIN2) genes have similar roles in signal trafficking, suggesting that a co-evolving gene cluster located on the chromosome 22 is under strong artificial selection in racehorses
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Quantitative Trait Loci
|
| 650 |
|
4 |
|a Racehorse
|
| 650 |
|
4 |
|a Selective Sweep
|
| 650 |
|
4 |
|a Single Nucleotide Polymorphism
|
| 700 |
1 |
|
|a Lee, Jin Woo
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Shin, Donghyun
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Shin, Kwang-Yun
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Kim, Jun
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Choi, Ik-Young
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Kim, Jaemin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Kim, Heebal
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Asian-Australasian journal of animal sciences
|d 1998
|g 28(2015), 11 vom: 03. Nov., Seite 1525-31
|w (DE-627)NLM098195883
|x 1011-2367
|7 nnns
|
| 773 |
1 |
8 |
|g volume:28
|g year:2015
|g number:11
|g day:03
|g month:11
|g pages:1525-31
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.5713/ajas.14.0696
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 28
|j 2015
|e 11
|b 03
|c 11
|h 1525-31
|