Tools to discriminate between targets of CK2 vs PLK2/PLK3 acidophilic kinases
While the great majority of Ser/Thr protein kinases are basophilic or proline directed, a tiny minority is acidophilic. The most striking example of such "acidophilic" kinases is CK2, whose sites are specified by numerous acidic residues surrounding the target one. However PLK2 and PLK3 ki...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1991. - 53(2012), 1 vom: 01. Juli
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| 1. Verfasser: |
Salvi, M
(VerfasserIn) |
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| Weitere Verfasser: |
Trashi, E,
Cozza, G,
Negro, A,
Hanson, P I,
Pinna, L A |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2012
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
CK2
PLK2
PLK3
acidophilic kinase
BI 2536
Buffers
Naphthyridines
Phenazines
mehr...
Protein Kinase Inhibitors
Pteridines
silmitasertib
C6RWP0N0L2
Protein Serine-Threonine Kinases
EC 2.7.11.1 |
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