Single tumor imaging with multiple antibodies targeting different antigens

Antibodies are important drugs for treating cancer and there is strong rationale for using multiple antibodies to improve outcomes. We labeled two breast cancer binding antibodies, anti-ErbB2 and anti-EpCAM, with infrared fluorescence dyes of different wavelengths and determined their in vivo distri...

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Veröffentlicht in:	BioTechniques. - 1993. - 52(2012), 4 vom: 01. Apr.
1. Verfasser:	Sun, Yujing (VerfasserIn)
Weitere Verfasser:	Shukla, Girja, Pero, Stephanie C, Currier, Erika, Sholler, Giselle, Krag, David
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2012
Zugriff auf das übergeordnete Werk:	BioTechniques
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. antibody breast cancer combination administration mouse near-infrared fluorescence imaging xenograft Antibodies, Neoplasm mehr... Antigens, Neoplasm Cell Adhesion Molecules EPCAM protein, human Epithelial Cell Adhesion Molecule Fluorescent Dyes ERBB2 protein, human EC 2.7.10.1 Receptor, ErbB-2