Design of a mouse restraint for synchrotron-based computed tomography imaging

High-resolution computed tomography (CT) imaging of a live animal within a lead-lined synchrotron light hutch presents several unique challenges. In order to confirm that the animal is under a stable plane of anaesthesia, several physiological parameters (e.g. heart rate, arterial oxygen saturation,...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Journal of synchrotron radiation. - 1994. - 22(2015), 5 vom: 20. Sept., Seite 1297-300
1. Verfasser: Gagnon, Kenneth B (VerfasserIn)
Weitere Verfasser: Caine, Sally, Samadi, Nazanin, Martinson, Mercedes, van der Loop, Melanie, Alcorn, Jane, Chapman, L Dean, Belev, George, Nichol, Helen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Journal of synchrotron radiation
Schlagworte:Journal Article Research Support, Non-U.S. Gov't X-ray imaging anaesthesia computer-aided design remote physiological monitoring three-dimensional printing
LEADER 01000caa a22002652 4500
001 NLM251986837
003 DE-627
005 20250219003033.0
007 cr uuu---uuuuu
008 231224s2015 xx |||||o 00| ||eng c
024 7 |a 10.1107/S160057751501036X  |2 doi 
028 5 2 |a pubmed25n0839.xml 
035 |a (DE-627)NLM251986837 
035 |a (NLM)26289283 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Gagnon, Kenneth B  |e verfasserin  |4 aut 
245 1 0 |a Design of a mouse restraint for synchrotron-based computed tomography imaging 
264 1 |c 2015 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 07.06.2016 
500 |a Date Revised 20.08.2015 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a High-resolution computed tomography (CT) imaging of a live animal within a lead-lined synchrotron light hutch presents several unique challenges. In order to confirm that the animal is under a stable plane of anaesthesia, several physiological parameters (e.g. heart rate, arterial oxygen saturation, core body temperature and respiratory rate) must be remotely monitored from outside the imaging hutch. In addition, to properly scan the thoracic region using CT, the animal needs to be held in a vertical position perpendicular to the fixed angle of the X-ray beam and free to rotate 180°-360°. A new X-ray transparent mouse restraint designed and fabricated using computer-aided design software and three-dimensional rapid prototype printing has been successfully tested at the Biomedical Imaging and Therapy bending-magnet (BMIT-BM) beamline at the Canadian Light Source 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a X-ray imaging 
650 4 |a anaesthesia 
650 4 |a computer-aided design 
650 4 |a remote physiological monitoring 
650 4 |a three-dimensional printing 
700 1 |a Caine, Sally  |e verfasserin  |4 aut 
700 1 |a Samadi, Nazanin  |e verfasserin  |4 aut 
700 1 |a Martinson, Mercedes  |e verfasserin  |4 aut 
700 1 |a van der Loop, Melanie  |e verfasserin  |4 aut 
700 1 |a Alcorn, Jane  |e verfasserin  |4 aut 
700 1 |a Chapman, L Dean  |e verfasserin  |4 aut 
700 1 |a Belev, George  |e verfasserin  |4 aut 
700 1 |a Nichol, Helen  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Journal of synchrotron radiation  |d 1994  |g 22(2015), 5 vom: 20. Sept., Seite 1297-300  |w (DE-627)NLM09824129X  |x 1600-5775  |7 nnns 
773 1 8 |g volume:22  |g year:2015  |g number:5  |g day:20  |g month:09  |g pages:1297-300 
856 4 0 |u http://dx.doi.org/10.1107/S160057751501036X  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_40 
912 |a GBV_ILN_350 
912 |a GBV_ILN_2005 
951 |a AR 
952 |d 22  |j 2015  |e 5  |b 20  |c 09  |h 1297-300