Nanoparticle-Loaded Protein-Polymer Nanodroplets for Improved Stability and Conversion Efficiency in Ultrasound Imaging and Drug Delivery

© 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 37 vom: 07. Okt., Seite 5484-92
1. Verfasser: Lee, Jeong Yu (VerfasserIn)
Weitere Verfasser: Carugo, Dario, Crake, Calum, Owen, Joshua, de Saint Victor, Marie, Seth, Anjali, Coussios, Constantin, Stride, Eleanor
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't breast cancer chemotherapy microbubbles nanodroplets ultrasound Antineoplastic Agents Antineoplastic Agents, Phytogenic Drug Carriers mehr... Ferric Compounds Fluorocarbons Magnetite Nanoparticles Quaternary Ammonium Compounds Serum Albumin ferric oxide 1K09F3G675 Oleic Acid 2UMI9U37CP Polyethylene Glycols 3WJQ0SDW1A dodecyltrimethylammonium GT3793XV5S Paclitaxel P88XT4IS4D
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520 |a © 2015 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. 
520 |a A new formulation of volatile nanodroplets stabilized by a protein and polymer coating and loaded with magnetic nanoparticles is developed. The droplets show enhanced stability and phase conversion efficiency upon ultrasound exposure compared with existing formulations. Magnetic targeting, encapsulation, and release of an anticancer drug are demonstrated in vitro with a 40% improvement in cytotoxicity compared with free drug 
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650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a breast cancer 
650 4 |a chemotherapy 
650 4 |a microbubbles 
650 4 |a nanodroplets 
650 4 |a ultrasound 
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650 7 |a 1K09F3G675  |2 NLM 
650 7 |a Oleic Acid  |2 NLM 
650 7 |a 2UMI9U37CP  |2 NLM 
650 7 |a Polyethylene Glycols  |2 NLM 
650 7 |a 3WJQ0SDW1A  |2 NLM 
650 7 |a dodecyltrimethylammonium  |2 NLM 
650 7 |a GT3793XV5S  |2 NLM 
650 7 |a Paclitaxel  |2 NLM 
650 7 |a P88XT4IS4D  |2 NLM 
700 1 |a Carugo, Dario  |e verfasserin  |4 aut 
700 1 |a Crake, Calum  |e verfasserin  |4 aut 
700 1 |a Owen, Joshua  |e verfasserin  |4 aut 
700 1 |a de Saint Victor, Marie  |e verfasserin  |4 aut 
700 1 |a Seth, Anjali  |e verfasserin  |4 aut 
700 1 |a Coussios, Constantin  |e verfasserin  |4 aut 
700 1 |a Stride, Eleanor  |e verfasserin  |4 aut 
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