Neural Stem Cell Transplant-Induced Effect on Neurogenesis and Cognition in Alzheimer Tg2576 Mice Is Inhibited by Concomitant Treatment with Amyloid-Lowering or Cholinergic α7 Nicotinic Receptor Drugs

Stimulating regeneration in the brain has the potential to rescue neuronal networks and counteract progressive pathological changes in Alzheimer's disease (AD). This study investigated whether drugs with different mechanisms of action could enhance neurogenesis and improve cognition in mice rec...

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Veröffentlicht in:Neural plasticity. - 1998. - 2015(2015) vom: 01., Seite 370432
1. Verfasser: Lilja, Anna M (VerfasserIn)
Weitere Verfasser: Malmsten, Linn, Röjdner, Jennie, Voytenko, Larysa, Verkhratsky, Alexei, Ögren, Sven Ove, Nordberg, Agneta, Marutle, Amelia
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't (S)-(1-azabicyclo(2.2.2)oct-3-yl)carbamic acid (S)-1-(2-fluorophenyl) ethyl ester Amyloid beta-Peptides Carbamates Dcx protein, mouse Doublecortin Protein Nicotinic Agonists Quinuclidines alpha7 Nicotinic Acetylcholine Receptor mehr... Physostigmine 9U1VM840SP phenserine SUE285UG3S