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231224s2015 xx |||||o 00| ||eng c |
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7 |
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|a 10.3928/23258160-20150730-15
|2 doi
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|a pubmed25n0838.xml
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|a (DE-627)NLM251582124
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|a (NLM)26247461
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Yehoshua, Zohar
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Association Between Growth of Geographic Atrophy and the Complement Factor I Locus
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|c 2015
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 01.04.2016
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|a Date Revised 14.05.2021
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright 2015, SLACK Incorporated.
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|a The association between the growth of geographic atrophy (GA) and a single nucleotide polymorphism (SNP) in the complement factor I (CFI) locus was investigated in the COMPLETE trial. Growth of GA at 52 weeks in eyes without the CFI at-risk allele was slightly faster than the growth in eyes with the CFI at-risk allele (P ≥ .72). The authors of the current study found that in contrast to the faster growth rate reported in CFI-positive eyes from the MAHALO trial, the CFI positive eyes in the COMPLETE trial did not grow faster, and this analysis included 24 eyes that met the MAHALO eligibility criteria
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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|a CFH protein, human
|2 NLM
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| 650 |
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|a Complement C2
|2 NLM
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| 650 |
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|a Complement C3
|2 NLM
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|a Complement Factor H
|2 NLM
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| 650 |
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|a 80295-65-4
|2 NLM
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| 650 |
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|a CFI protein, human
|2 NLM
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| 650 |
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|a EC 3.4.21.45
|2 NLM
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| 650 |
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7 |
|a Complement Factor I
|2 NLM
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| 650 |
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7 |
|a EC 3.4.21.45
|2 NLM
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| 700 |
1 |
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|a de Amorim Garcia Filho, Carlos Alexandre
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Nunes, Renata Portella
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gregori, Giovanni
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Penha, Fernando M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Moshfeghi, Andrew A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Luo, Hongrong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kang, Zhang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sadda, SriniVas
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Feuer, William
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Rosenfeld, Philip J
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 46(2015), 7 vom: 14. Juli, Seite 772-4
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnns
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| 773 |
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|g volume:46
|g year:2015
|g number:7
|g day:14
|g month:07
|g pages:772-4
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|u http://dx.doi.org/10.3928/23258160-20150730-15
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